Immune Checkpoint Inhibitor–associated Myocarditis with Myasthenia Gravis: A Case Report

Immune checkpoint inhibitors (ICIs) have revolutionized the management of various cancers. However, myocarditis is a rare but severe complication associated with ICI use. We describe the case of a 62-year-old woman who presented with ICI-associated myocarditis alongside myasthenia gravis. Consequently, the patient was treated with initial high doses of corticosteroids combined with immunosuppressive therapy, and improved outcomes and clinical remission were observed. The overlap of myocarditis with myasthenia gravis is associated with high morbidity and mortality. The early administration of high dose of corticosteroids combined with immunosuppressive therapy was associated with improved outcomes in our patient.